2. Gene
  3. MIGA2 - mitoguardin 2 Gene

MIGA2 - mitoguardin 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FAM73B; C9orf54

Gene ID: 84895 | Gene type: protein coding

About MIGA2

Cytogenetic location: 9q34.11 Genomic coordinates (GRCh38): 9:129,036,626-129,072,082 (from NCBI)

This gene has 14 transcripts (splice variants), 207 orthologues and 1 paralogue. Ubiquitous expression in duodenum (RPKM 12.6), small intestine (RPKM 10.8) and 25 other tissues.

Summary

Enables protein heterodimerization activity and protein homodimerization activity. Involved in mitochondrial fusion. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

MIGA2 Products(2)

mRNA Protein Name
NM_001329990.2 NP_001316919.1 mitoguardin 2 isoform 2
NM_032809.4 NP_116198.3 mitoguardin 2 isoform 1

MIGA2 Protein Structure

Miga

Miga: Mitoguardin (31 - 568)

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  • 593 a.a.
Protein Preferred Names Protein Names

mitoguardin 2

family with sequence similarity 73, member B

Related Diseases

Diseases Alias
Pontocerebellar Hypoplasia, Type 10

Pontocerebellar Hypoplasia Type 10

PCH10

Clp1-Related Pontocerebellar Hypoplasia

Pontocerebellar Hypoplasia 10

Hypoplasia, Pontocerebellar, Type 10
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08447 MIGA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta MIGA2 VGNC VGNC:74812
Canis familiaris MIGA2 VGNC VGNC:43233
Mus musculus MIGA2 MGD MGI:1922035
Rattus norvegicus MIGA2 RGD RGD:1310887
Felis catus MIGA2 VGNC VGNC:63505
Bos taurus MIGA2 VGNC VGNC:31474