KRT36 - keratin 36 Gene

Homo sapiens

Also known as HA6; hHa6; KRTHA6

Gene ID: 8689 | Gene type: protein coding

About KRT36

Cytogenetic location: 17q21.2 Genomic coordinates (GRCh38): 17:41,486,136-41,489,910 (from NCBI)

This gene has 2 transcripts (splice variants), 116 orthologues and 68 paralogues. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]

KRT36 Products(1)

mRNA	Protein	Name
NM_003771.5	NP_003762.1	keratin, type I cuticular Ha6

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in keratin filament	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KRT36 Protein Structure

Filament

0
100
200
300
400
467 a.a.

Protein Preferred Names

Protein Names

keratin, type I cuticular Ha6

K36

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07453	KRT36 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	KRT36	VGNC	VGNC:42527
Macaca mulatta	KRT36	VGNC	VGNC:74218
Mus musculus	KRT36	MGD	MGI:109364
Felis catus	KRT36	VGNC	VGNC:107258
Bos taurus	KRT36	VGNC	VGNC:30730
Rattus norvegicus	KRT36	RGD	RGD:1305792

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