LMLN - leishmanolysin like peptidase Gene

Homo sapiens

Also known as INV; MSP; GP63; IX14; LMNL1

Gene ID: 89782 | Gene type: protein coding

About LMLN

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:197,960,217-198,043,720 (from NCBI)

This gene has 11 transcripts (splice variants) and 193 orthologues. Broad expression in testis (RPKM 8.5), thyroid (RPKM 4.0) and 25 other tissues.

Summary

This gene encodes a zinc-metallopeptidase. The encoded protein may play a role in cell migration and invasion. Studies of a similar protein in Drosophila indicate a potential role in mitotic progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]

LMLN Products(2)

mRNA	Protein	Name
NM_001136049.3	NP_001129521.3	leishmanolysin-like peptidase isoform 1 precursor
NM_033029.4	NP_149018.3	leishmanolysin-like peptidase isoform 2 precursor

LMLN Protein Structure

Peptidase_M8

0
200
400
600
655 a.a.

Protein Preferred Names

Protein Names

leishmanolysin-like peptidase

invadolysin

Related Diseases

Diseases

Alias

Leishmaniasis

Post-Kala-Azar Dermal Leishmaniasis	Post Kala-Azar Dermal Leishmaniasis
Post-Kala-Azar Dermal Infectious Disease By Leishmaniasis	Cutaneous Leishmaniasis
Kala-Azar	Visceral Leishmaniasis
Leishmaniasis, Cutaneous	Leishmaniasis, Visceral
Leishmania	Leishmania Infection
Leishmaniosis

Cutaneous Leishmaniasis

Diffuse Cutaneous Leishmaniasis	Asian Desert Cutaneous Leishmaniasis
Leishmaniasis, Cutaneous	Leproid Leishmaniasis
Leishmaniasis Diffuse Cutaneous	Leishmaniasis Cutaneous
Ethiopian Cutaneous Leishmaniasis	Old World Cutaneous Leishmaniasis

Visceral Leishmaniasis

Kala-Azar	Leishmaniasis, Visceral
Infection By Visceral Leishmaniasis	Leishmaniasis Visceral
Sahib Disease	Ponos
Burdwan Fever	Mard El Bicha
Sirkari Disease	Indian Visceral Leishmaniasis
Dumdum Fever	Visceral Leishmaniasis Due To Leishmania Donovani

Mucocutaneous Leishmaniasis

American Cutaneous Leishmaniasis	American Mucocutaneous Leishmaniasis
Cutaneous Leishmaniasis, American	Mucocutaneous Leishmaniasis, American
New World Cutaneous Leishmaniasis	Leishmaniasis, Mucocutaneous
Espundia	Leishmania Braziliensis Infection

Splenic Disease

Splenic Diseases	Dyssplenism
Spleen Disease	Abnormality Of The Spleen
Spleen Diseases

Rapp-Hodgkin Syndrome

RHS	Anhidrotic Ectodermal Dysplasia With Cleft Lip/Palate
Ectodermal Dysplasia, Rapp-Hodgkin Type	Rapp-Hodgkin Ectodermal Dysplasia Syndrome
Ectodermal Dysplasia, Anhidrotic, With Cleft Lip/Palate	Ectodermal Dysplasia Syndrome, Rapp-Hodgkin Type
Edrh	Rapp-Hodgkin Ectodermal Dysplasia
Orofacial Cleft 8

Erysipeloid

Infection Due To Erysipelothrix Rhusiopathiae

Erysipelothrix Infection

Trichomoniasis

Trichomonas Infection	Trichomonas Infections
Disease Due To Trichomonadidae	Infection By Trichomonas
Trichomonadosis	Trichomonas Pruritus
Trichomonosis	Tricomoniasis

Parasitic Protozoa Infectious Disease

Protozoan Infections	Mastigophora Infectious Disease
Sarcomastigophora Infectious Disease

Megaesophagus

Esophageal Achalasia

Arthrogryposis Multiplex Congenita 2, Neurogenic Type

Arthrogryposis Multiplex Congenita, Neurogenic Type	Amcn
Arthrogryposis Multiplex Congenita Neurogenic Type	AMC2
Amc, Neurogenic Type	Neurogenic-Type Arthrogryposis Multiplex Congenita-2
Amc Neurogenic Type	Neurogenic Type Of Amc
Neurogenic Arthrogryposis Multiplex Congenita	Arthrogryposis Multiplex Congenita, Neurogenic

Sleeping Sickness

African Trypanosomiasis	African Sleeping Sickness
Trypanosomiasis, Human East-African	Trypanosomiasis, East African
Trypanosomiasis African	Trypanosomiasis, African
Human African Trypanosomiasis

Trypanosomiasis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07713	LMLN Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	LMLN	MGD	MGI:2444736
Bos taurus	LMLN	VGNC	VGNC:30928
Canis familiaris	LMLN	VGNC	VGNC:42716
Felis catus	LMLN	VGNC	VGNC:63251
Macaca mulatta	LMLN	VGNC	VGNC:74296
Rattus norvegicus	LMLN	RGD	RGD:1311465

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