ATG16L2 - autophagy related 16 like 2 Gene

Homo sapiens

Also known as WDR80; ATG16B

Gene ID: 89849 | Gene type: protein coding

About ATG16L2

Cytogenetic location: 11q13.4 Genomic coordinates (GRCh38): 11:72,814,411-72,843,740 (from NCBI)

This gene has 21 transcripts (splice variants), 171 orthologues and 1 paralogue. Broad expression in spleen (RPKM 22.5), skin (RPKM 19.9) and 24 other tissues.

Summary

Predicted to be involved in autophagosome assembly and negative stranded viral RNA replication. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ATG16L2 Products(2)

mRNA	Protein	Name
NM_001318766.2	NP_001305695.1	protein Atg16l2 isoform 2
NM_033388.2	NP_203746.1	protein Atg16l2 isoform 1

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
part of Atg12-Atg5-Atg16 complex	IPI IPI: Inferred from physical interaction	23202584	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ATG16L2 Protein Structure

ATG16

WD40

0
100
200
300
400
500
619 a.a.

Protein Preferred Names

Protein Names

protein Atg16l2

APG16-like 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01144	ATG16L2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ATG16L2	VGNC	VGNC:38220
Mus musculus	ATG16L2	MGD	MGI:1920933
Macaca mulatta	ATG16L2	VGNC	VGNC:70130
Rattus norvegicus	ATG16L2	RGD	RGD:1311400
Felis catus	ATG16L2	VGNC	VGNC:59999
Bos taurus	ATG16L2	VGNC	VGNC:26254

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