2. Gene
  3. TMEM259 - transmembrane protein 259 Gene

TMEM259 - transmembrane protein 259 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as MBRL; ASBABP1; C19orf6; R32184_3; MEMBRALIN

Gene ID: 91304 | Gene type: protein coding

About TMEM259

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,009,653-1,021,123 (from NCBI)

This gene has 12 transcripts (splice variants), 190 orthologues and 1 paralogue. Ubiquitous expression in spleen (RPKM 49.2), fat (RPKM 38.4) and 25 other tissues.

Summary

Predicted to be involved in positive regulation of ERAD pathway and response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

TMEM259 Products(2)

mRNA Protein Name
NM_001033026.2 NP_001028198.1 membralin isoform 1
NM_033420.4 NP_219488.1 membralin isoform 2

TMEM259 Protein Structure

Membralin

Membralin: Tumour-associated protein (34 - 402)

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  • 620 a.a.
Protein Preferred Names Protein Names

membralin

aspecific BCL2 ARE-binding protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14712 TMEM259 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TMEM259 MGD MGI:2177957
Rattus norvegicus TMEM259 RGD RGD:1311136
Canis familiaris TMEM259 VGNC VGNC:47561
Felis catus TMEM259 VGNC VGNC:80739
Bos taurus TMEM259 VGNC VGNC:36067