PDCD5 - programmed cell death 5 Gene

Homo sapiens

Also known as TFAR19

Gene ID: 9141 | Gene type: protein coding

About PDCD5

Cytogenetic location: 19q13.11 Genomic coordinates (GRCh38): 19:32,581,190-32,587,453 (from NCBI)

This gene has 8 transcripts (splice variants) and 222 orthologues. Ubiquitous expression in testis (RPKM 17.5), adrenal (RPKM 13.5) and 25 other tissues.

Summary

This gene encodes a protein that is upregulated during Apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010]

PDCD5 Products(1)

mRNA	Protein	Name
NM_004708.4	NP_004699.1	programmed cell death protein 5

PDCD5 Protein Structure

dsDNA_bind

0
100
125 a.a.

Protein Preferred Names

Protein Names

programmed cell death protein 5

TF-1 cell apoptosis-related protein 19

Recombinant PDCD5 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71019	PDCD5 Protein, Human (His)	O14737 (M1-Y125)	≥95%

Related Diseases

Diseases

Alias

Fibrolamellar Carcinoma

Fibrolamellar Hepatocellular Carcinoma	Fhcc
Fibrolamellar Hepatocarcinoma	Hepatocellular Carcinoma, Fibrolamellar
Oncocytic Hepatocellular Tumor	Eosinophilic Glassy Cell Hepatoma
Eosinophilic Hepatocellular Carcinoma With Lamellar Fibrosis	Fl-Hcc
Fibrolamellar Oncocytic Hepatoma	Hepatocellular Carcinoma With Increased Stromal Fibrosis
Polygonal Cell Hepatocellular Carcinoma With Fibrous Stroma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10193	PDCD5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	PDCD5	MGD	MGI:1913538
Rattus norvegicus	PDCD5	RGD	RGD:1310561
Bos taurus	PDCD5	VGNC	VGNC:32662
Felis catus	PDCD5	VGNC	VGNC:68745
Canis familiaris	PDCD5	VGNC	VGNC:44339
Others	PDCD5	NCBI

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