SLC25A51 - solute carrier family 25 member 51 Gene

Homo sapiens

Also known as CG7943; MCART1

Gene ID: 92014 | Gene type: protein coding

About SLC25A51

Cytogenetic location: 9p13.2-p13.1 Genomic coordinates (GRCh38): 9:37,877,575-37,904,127 (from NCBI)

This gene has 3 transcripts (splice variants), 101 orthologues and 49 paralogues. Ubiquitous expression in fat (RPKM 3.6), testis (RPKM 1.8) and 25 other tissues.

Summary

Enables NAD transmembrane transporter activity. Involved in mitochondrial NAD transmembrane transport. Located in mitochondrion. Is active in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC25A51 Products(1)

mRNA	Protein	Name
NM_033412.4	NP_219480.1	mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables NAD transmembrane transporter activity	IDA IDA: Inferred from direct assay	32906142	GOA
enables NAD transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	33087354	GOA

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of aerobic electron transport chain	IMP IMP: Inferred from mutant phenotype	33262325	GOA
involved in aerobic electron transport chain	IMP IMP: Inferred from mutant phenotype	33087354	GOA
involved in mitochondrial NAD transmembrane transport	IDA IDA: Inferred from direct assay	32906142	GOA
involved in mitochondrial NAD transmembrane transport	IMP IMP: Inferred from mutant phenotype	33087354	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
is active in mitochondrial inner membrane	IDA IDA: Inferred from direct assay	33087354	GOA
located in mitochondrion	IDA IDA: Inferred from direct assay	32906142	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC25A51 Protein Structure

Mito_carr

0
100
200
297 a.a.

Protein Preferred Names

Protein Names

mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

mitochondrial NAD(+) transporter SLC25A51

Related Diseases

Diseases

Alias

Mitochondrial Dna Depletion Syndrome 12a

Bladder Small Cell Carcinoma

Small Cell Bladder Cancer	Small Cell Carcinoma Of The Bladder
Poorly Differentiated Neuroendocrine Carcinoma Of The Bladder	Sccb
Small Cell Bladder Carcinoma	Small Cell Carcinoma Of The Urinary Bladder

Phototoxic Dermatitis

Dermatitis, Phototoxic	Photosensitisation Reaction
Photosensitive Dermatitis	Photosensitiveness

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13132	SLC25A51 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SLC25A51	MGD	MGI:2684984

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