2. Gene
  3. ASB16 - ankyrin repeat and SOCS box containing 16 Gene

ASB16 - ankyrin repeat and SOCS box containing 16 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 92591 | Gene type: protein coding

About ASB16

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:44,170,704-44,179,084 (from NCBI)

This gene has 3 transcripts (splice variants), 186 orthologues and 7 paralogues. Ubiquitous expression in spleen (RPKM 1.6), prostate (RPKM 1.5) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Jul 2008]

ASB16 Products(1)

mRNA Protein Name
NM_080863.5 NP_543139.4 ankyrin repeat and SOCS box protein 16
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17474147 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ASB16 Protein Structure

Ank

Ank: Ankyrin repeat (114 - 140)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (147 - 239)

Ank_5

Ank_5: Ankyrin repeats (many copies) (270 - 324)

SOCS_box

SOCS_box: SOCS box (408 - 446)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 453 a.a.
Protein Preferred Names Protein Names

ankyrin repeat and SOCS box protein 16

ankyrin repeat and SOCS box-containing protein 16

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01065 ASB16 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W250197 ASB-16 / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ASB16 RGD RGD:1563878
Canis familiaris ASB16 VGNC VGNC:38160
Macaca mulatta ASB16 VGNC VGNC:99119
Mus musculus ASB16 MGD MGI:2654437
Bos taurus ASB16 VGNC VGNC:26193
Felis catus ASB16 VGNC VGNC:98762