2. Gene
  3. LRRC4B - leucine rich repeat containing 4B Gene

LRRC4B - leucine rich repeat containing 4B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HSM; LRIG4; NGL-3

Gene ID: 94030 | Gene type: protein coding

About LRRC4B

This gene has 4 transcripts (splice variants), 256 orthologues and 22 paralogues. Biased expression in brain (RPKM 11.1), endometrium (RPKM 2.3) and 4 other tissues.

Summary

Predicted to enable signaling receptor binding activity. Predicted to be involved in regulation of synapse assembly and synaptic membrane adhesion. Predicted to be located in cerebellar mossy fiber and presynaptic membrane. Predicted to be active in glutamatergic synapse and plasma membrane. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022]

LRRC4B Products(2)

mRNA Protein Name
NM_001080457.2 NP_001073926.1 leucine-rich repeat-containing protein 4B precursor
NM_001348568.1 NP_001335497.1 leucine-rich repeat-containing protein 4B precursor

LRRC4B Protein Structure

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (57 - 85)

LRR_5

LRR_5: Leucine rich repeats (6 copies) (101 - 223)

LRR_1

LRR_1: Leucine Rich Repeat (230 - 252)

LRR_8

LRR_8: Leucine rich repeat (253 - 311)

I-set

I-set: Immunoglobulin I-set domain (364 - 453)

  • 0
  • 200
  • 400
  • 600
  • 713 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat-containing protein 4B

leucine-rich repeats and immunoglobulin-like domains 4

Related Diseases

Diseases Alias
Childhood Infratentorial Ependymoma

Pediatric Infratentorial Ependymoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07821 LRRC4B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta LRRC4B VGNC VGNC:74350
Canis familiaris LRRC4B VGNC VGNC:42802
Bos taurus LRRC4B VGNC VGNC:31019
Mus musculus LRRC4B MGD MGI:3027390
Rattus norvegicus LRRC4B RGD RGD:1307121