SYTL3 - synaptotagmin like 3 Gene

Homo sapiens

Also known as SLP3

Gene ID: 94120 | Gene type: protein coding

About SYTL3

This gene has 4 transcripts (splice variants), 157 orthologues and 31 paralogues. Ubiquitous expression in thyroid (RPKM 15.0), small intestine (RPKM 10.0) and 25 other tissues.

Summary

The protein encoded by this gene belongs to a family of peripheral membrane proteins that play a role in vesicular trafficking. This protein binds Phospholipids in the presence of calcium ions. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

SYTL3 Products(5)

mRNA	Protein	Name
NM_001009991.4	NP_001009991.2	synaptotagmin-like protein 3 isoform 2
NM_001242384.2	NP_001229313.1	synaptotagmin-like protein 3 isoform 1
NM_001242394.2	NP_001229323.1	synaptotagmin-like protein 3 isoform 1
NM_001242395.2	NP_001229324.1	synaptotagmin-like protein 3 isoform 2
NM_001318745.2	NP_001305674.1	synaptotagmin-like protein 3 isoform 3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SYTL3 Protein Structure

FYVE_2

0
100
200
300
400
500
610 a.a.

Protein Preferred Names

Protein Names

synaptotagmin-like protein 3

exophilin-6

Related Diseases

Diseases

Alias

Griscelli Syndrome

Chediak-Higashi-Like Syndrome	Griscelli-Prunieras Syndrome
Partial Albinism-Immunodeficiency Syndrome	Griscelli Disease
Gs	Hypopigmentation Immunodeficiency Disease
Partial Albinism With Immunodeficiency	Immunodeficiency Syndrome With Hypopigmentation
Hypopigmentation-Immunodeficiency Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14124	SYTL3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SYTL3	VGNC	VGNC:47052
Bos taurus	SYTL3	VGNC	VGNC:35547
Mus musculus	SYTL3	MGD	MGI:1933367
Felis catus	SYTL3	VGNC	VGNC:65906
Rattus norvegicus	SYTL3	RGD	RGD:1561992
Macaca mulatta	SYTL3	VGNC	VGNC:104431

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