2. Gene
  3. GNG8 - G protein subunit gamma 8 Gene

GNG8 - G protein subunit gamma 8 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HG3E

Gene ID: 94235 | Gene type: protein coding

About GNG8

This gene has 2 transcripts (splice variants), 168 orthologues and 11 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within cellular response to pheromone; nose development; and social behavior. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. [provided by Alliance of Genome Resources, Apr 2022]

GNG8 Products(1)

mRNA Protein Name
NM_033258.2 NP_150283.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23773523 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GNG8 Protein Structure

G-gamma

G-gamma: GGL domain (10 - 69)

  • 0
  • 70 a.a.
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

gamma-9

Related Diseases

Diseases Alias
Adenosquamous Lung Carcinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05561 GNG8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GNG8 RGD RGD:620808
Mus musculus GNG8 MGD MGI:109163
Bos taurus GNG8 VGNC VGNC:29469
Canis familiaris GNG8 VGNC VGNC:41323