STARD8 - StAR related lipid transfer domain containing 8 Gene

Homo sapiens

Also known as DLC3; ARHGAP38; STARTGAP3

Gene ID: 9754 | Gene type: protein coding

About STARD8

Cytogenetic location: Xq13.1 Genomic coordinates (GRCh38): X:68,647,666-68,725,836 (from NCBI)

This gene has 5 transcripts (splice variants), 151 orthologues and 2 paralogues. Broad expression in kidney (RPKM 8.5), fat (RPKM 6.6) and 24 other tissues.

Summary

This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor. [provided by RefSeq, Mar 2010]

STARD8 Products(3)

mRNA	Protein	Name
NM_001142503.3	NP_001135975.1	stAR-related lipid transfer protein 8 isoform a
NM_001142504.3	NP_001135976.1	stAR-related lipid transfer protein 8 isoform b
NM_014725.5	NP_055540.2	stAR-related lipid transfer protein 8 isoform b

STARD8 Protein Structure

RhoGAP

START

0
200
400
600
800
1023 a.a.

Protein Preferred Names

Protein Names

stAR-related lipid transfer protein 8

START domain containing 8

Related Diseases

Diseases

Alias

Craniofrontonasal Syndrome

Craniofrontonasal Dysplasia	CFNS
Cfnd	Craniofrontonasal Dysostosis
Craniofrontonasal Dystosis	Dysplasia, Craniofrontonasal

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13884	STARD8 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	STARD8	VGNC	VGNC:77961
Canis familiaris	STARD8	VGNC	VGNC:46888
Felis catus	STARD8	VGNC	VGNC:65758
Mus musculus	STARD8	MGD	MGI:2448556
Bos taurus	STARD8	VGNC	VGNC:35369
Rattus norvegicus	STARD8	RGD	RGD:1560770

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