2. Gene
  3. TM9SF4 - transmembrane 9 superfamily member 4 Gene

TM9SF4 - transmembrane 9 superfamily member 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as dJ836N17.2

Gene ID: 9777 | Gene type: protein coding

About TM9SF4

Cytogenetic location: 20q11.21 Genomic coordinates (GRCh38): 20:32,109,714-32,167,256 (from NCBI)

This gene has 7 transcripts (splice variants), 213 orthologues and 3 paralogues. Ubiquitous expression in placenta (RPKM 20.7), brain (RPKM 16.4) and 25 other tissues.

Summary

Involved in several processes, including positive regulation of protein localization; regulation of intracellular pH; and vacuolar proton-transporting V-type ATPase complex assembly. Located in Golgi apparatus and early endosome. [provided by Alliance of Genome Resources, Apr 2022]

TM9SF4 Products(2)

mRNA Protein Name
NM_001363731.2 NP_001350660.1 transmembrane 9 superfamily member 4 isoform 2
NM_014742.4 NP_055557.2 transmembrane 9 superfamily member 4 isoform 1 precursor

TM9SF4 Protein Structure

EMP70

EMP70: Endomembrane protein 70 (54 - 600)

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  • 642 a.a.
Protein Preferred Names Protein Names

transmembrane 9 superfamily member 4

dinucleotide oxidase disulfide thiol exchanger 3 superfamily member 4

Related Diseases

Diseases Alias
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14615 TM9SF4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TM9SF4 VGNC VGNC:66230
Canis familiaris TM9SF4 VGNC VGNC:47417
Bos taurus TM9SF4 VGNC VGNC:35913
Rattus norvegicus TM9SF4 RGD RGD:1307768
Macaca mulatta TM9SF4 VGNC VGNC:79883
Mus musculus TM9SF4 MGD MGI:2139220