2. Gene
  3. TRIL - TLR4 interactor with leucine rich repeats Gene

TRIL - TLR4 interactor with leucine rich repeats Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 9865 | Gene type: protein coding

About TRIL

Cytogenetic location: 7p14.3 Genomic coordinates (GRCh38): 7:28,953,358-28,958,330 (from NCBI)

This gene has 1 transcript (splice variant), 179 orthologues and 22 paralogues.

Summary

TRIL is a component of the TLR4 (MIM 603030) complex and is induced in a number of cell types by lipopolysaccharide (LPS) (Carpenter et al., 2009 [PubMed 19710467]).[supplied by OMIM, Apr 2010]

TRIL Products(1)

mRNA Protein Name
NM_014817.4 NP_055632.2 TLR4 interactor with leucine rich repeats precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables lipopolysaccharide binding IDA
IDA: Inferred from direct assay
19710467 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
35253622 GOA
Biological Process GO Annotation Evidence Reference Source
involved in regulation of cytokine production involved in immune response IDA
IDA: Inferred from direct assay
19710467 GOA
involved in toll-like receptor 4 signaling pathway IDA
IDA: Inferred from direct assay
19710467 GOA
Cellular Component GO Annotation Evidence Reference Source
part of lipopolysaccharide receptor complex IDA
IDA: Inferred from direct assay
19710467 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TLR4 interactor with leucine rich repeats

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15018 TRIL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TRIL MGD MGI:1914123
Canis familiaris TRIL VGNC VGNC:47803
Macaca mulatta TRIL VGNC VGNC:79345
Rattus norvegicus TRIL RGD RGD:1310827
Bos taurus TRIL VGNC VGNC:36311
Others TRIL NCBI