RBM19 - RNA binding motif protein 19 Gene

Homo sapiens

Also known as Mrd1

Gene ID: 9904 | Gene type: protein coding

About RBM19

Cytogenetic location: 12q24.13-q24.21 Genomic coordinates (GRCh38): 12:113,816,740-113,966,325 (from NCBI)

This gene has 7 transcripts (splice variants), 191 orthologues and 36 paralogues. Ubiquitous expression in testis (RPKM 6.2), spleen (RPKM 5.9) and 25 other tissues.

Summary

This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009]

RBM19 Products(3)

mRNA	Protein	Name
NM_001146698.2	NP_001140170.1	probable RNA-binding protein 19
NM_001146699.2	NP_001140171.1	probable RNA-binding protein 19
NM_016196.4	NP_057280.2	probable RNA-binding protein 19

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleolus	IDA IDA: Inferred from direct assay	16027046	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RBM19 Protein Structure

RRM_1

0
200
400
600
800
960 a.a.

Protein Preferred Names

Protein Names

probable RNA-binding protein 19

Related Diseases

Diseases

Alias

Ulnar-Mammary Syndrome

Schinzel Syndrome	UMS
Pallister Ulnar-Mammary Syndrome	Ulnar-Mammary Syndrome Of Pallister

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect Pre-designed Sets	Purity	Rare Diseases Unkown
HY-RS11738	RBM19 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	RBM19	VGNC	VGNC:33790
Rattus norvegicus	RBM19	RGD	RGD:1308928
Canis familiaris	RBM19	VGNC	VGNC:45413
Macaca mulatta	RBM19	VGNC	VGNC:76559
Mus musculus	RBM19	MGD	MGI:1921361
Felis catus	RBM19	VGNC	VGNC:64523

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