Tiparp - TCDD-inducible poly(ADP-ribose) polymerase Gene

Mus musculus

Also known as PARP7; ARTD14

Gene ID: 99929 | Gene type: protein coding

About Tiparp

Chromosome 3: 65,435,831-65,462,939 forward strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 208 orthologues, 7 paralogues and is associated with 68 phenotypes. Ubiquitous expression in bladder adult (RPKM 8.4), genital fat pad adult (RPKM 4.9) and 28 other tissues.

Summary

Enables NAD+ ADP-ribosyltransferase activity. Acts upstream of or within several processes, including animal organ development; cellular hormone metabolic process; and face morphogenesis. Predicted to be located in nucleus. Is expressed in bladder; reproductive system; telencephalon; and tongue. Orthologous to human TIPARP (TCDD inducible poly(ADP-ribose) polymerase). [provided by Alliance of Genome Resources, Apr 2022]

Tiparp Products(1)

mRNA	Protein	Name
NM_178892.5	NP_849223.2	protein mono-ADP-ribosyltransferase TIPARP

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables NAD+-protein poly-ADP-ribosyltransferase activity	IDA IDA: Inferred from direct assay	23275542	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within androgen metabolic process	IMP IMP: Inferred from mutant phenotype	19056881	MGI
acts upstream of or within estrogen metabolic process	IMP IMP: Inferred from mutant phenotype	19056881	MGI
acts upstream of or within excretion	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within face morphogenesis	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within female gonad development	IMP IMP: Inferred from mutant phenotype	19056881	MGI
acts upstream of or within hemopoiesis	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within kidney development	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within metabolic process	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within platelet-derived growth factor receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within post-embryonic development	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within roof of mouth development	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within skeletal system morphogenesis	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within smooth muscle tissue development	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within vasculogenesis	IMP IMP: Inferred from mutant phenotype	17143286	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Tiparp Protein Structure

WWE

TCCD_inducible_PARP_like

0
200
400
600
657 a.a.

Protein Preferred Names

Protein Names

protein mono-ADP-ribosyltransferase TIPARP

ADP-ribosyltransferase diphtheria toxin-like 14

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS14546	TIPARP Human Pre-designed siRNA Set A	/	Unkown
HY-RS14547	Tiparp Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS14548	Tiparp Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tiparp	NCBI	NCBI:25976

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