2. GPCR/G Protein
  3. GHSR
  4. GHSR-1a agonist-1

GHSR-1a agonist-1 (Compound 4b) is an orally active agonist of the human growth hormone secretagogue receptor 1a (GHSR-1a), with an EC50 of 0.49 nM. GHSR-1a agonist-1 can effectively stimulate the release of endogenous growth hormone by activating GHSR-1a. GHSR-1a agonist-1 administered orally at a dose as low as 0.1 mg/kg can increase the body weight and body length of 4-week-old rats. GHSR-1a agonist-1 can be used in the research field of growth and development retardation in children.

For research use only. We do not sell to patients.

GHSR-1a agonist-1 Chemical Structure

GHSR-1a agonist-1 Chemical Structure

CAS No. : 3060887-25-1

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GHSR-1a agonist-1 Related Antibodies

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GHSR1a

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Description

GHSR-1a agonist-1 (Compound 4b) is an orally active agonist of the human growth hormone secretagogue receptor 1a (GHSR-1a), with an EC50 of 0.49 nM. GHSR-1a agonist-1 can effectively stimulate the release of endogenous growth hormone by activating GHSR-1a. GHSR-1a agonist-1 administered orally at a dose as low as 0.1 mg/kg can increase the body weight and body length of 4-week-old rats. GHSR-1a agonist-1 can be used in the research field of growth and development retardation in children[1].

IC50 & Target

GHSR1a

0.49 nM (IC50)

Molecular Weight

531.65

Formula

C30H37N5O4
CAS No.
SMILES

O=C(N(CCC1=NN(C2=O)C3CC3)C[C@]12CC4=CC=CC=C4)[C@@H](COCC5=CC=CC=C5)NC(C(N)(C)C)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GHSR-1a agonist-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GHSR-1a agonist-13060887-25-1GHSRGrowth hormone secretagogue receptorGhrelin receptorInhibitorinhibitorinhibit

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