1. PROTAC
  2. Ligands for Target Protein for PROTAC
  3. GID4 Ligand 2

GID4 Ligand 2 (compound 67) is a selective GID4 binder (IC50=18.9 μM; Kd=17 μM). GID4 Ligand 2 can be used for the synthesis of PROTACs.

For research use only. We do not sell to patients.

GID4 Ligand 2 Chemical Structure

GID4 Ligand 2 Chemical Structure

CAS No. : 3031442-90-4

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Description

GID4 Ligand 2 (compound 67) is a selective GID4 binder (IC50=18.9 μM; Kd=17 μM). GID4 Ligand 2 can be used for the synthesis of PROTACs[1].

IC50 & Target

IC50: 18.9 μM (GID4)[1].

In Vitro

GID4 Ligand 1 (50 μM; 10 min) binds GID4 in lysates of HEK293 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: HEK293 cells (expressing FLAG-GID4)
Concentration: 50 μM
Incubation Time: 10 min
Result: Produced a Tm shift of 3.8°C.
Molecular Weight

224.30

Formula

C15H16N2

CAS No.
SMILES

NC1=CC=CC2=C1CCNC2C3=CC=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
GID4 Ligand 2
Cat. No.:
HY-151476
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