GLP-1R agonist 22

Cat. No.: HY-162437: FAQs
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GLP-1R agonist 22 (Compound I-135) is an agonist for glucagon-like peptide-1 receptor (GLP-1 receptor), with EC₅₀ of 0.0165 nM.

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GLP-1R agonist 22 Chemical Structure

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Description	GLP-1R agonist 22 (Compound I-135) is an agonist for glucagon-like peptide-1 receptor (GLP-1 receptor), with EC₅₀ of 0.0165 nM^[1].
Molecular Weight	576.02
Formula	C₃₀H₂₇ClFN₅O₄
SMILES	ClC1=CC(F)=C(COC2=C(C#N)C=C(CCN(CC3=NC4=CC=C(C(O)=O)C=C4N3C[C@@H]5CCO5)[C@H]6C)C6=N2)C=C1
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (265 KB) Handling Instructions (2659 KB)
References	[1]. Kitamura FY, et al., Fused ring compound having glp-1 receptor agonist effect. WO2024063143A1.

GLP-1R agonist 22 Related Classifications

Metabolic Disease

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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GLP-1R agonist 22

GLP-1R agonist 22 Related Antibodies

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