Glucocorticoid receptor drug-linke 1

Cat. No.: HY-170587 Purity: 96.01%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

Glucocorticoid receptor drug-linke 1 is a drug-linker conjugate, that can be used for synthesis of BDCA2-targeting ADC.

For research use only. We do not sell to patients.

Glucocorticoid receptor drug-linke 1 Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All Drug-Linker Conjugates for ADC Isoform Specific Products:

View All Isoforms

Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

Biological Activity
Purity & Documentation
References
Customer Review

Description

Glucocorticoid receptor drug-linke 1 is a drug-linker conjugate, that can be used for synthesis of BDCA2-targeting ADC^[1].

Molecular Weight

649.67

Formula

C₃₅H₄₀NO₉P

CAS No.

3048601-02-8

Appearance

Solid

Color

White to off-white

SMILES

O=P(O)(O)OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@@H](C6=CC=C(C=C6)CC7=CC(N)=CC=C7)O2)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (153.92 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5392 mL	7.6962 mL	15.3924 mL
5 mM	0.3078 mL	1.5392 mL	3.0785 mL
10 mM	0.1539 mL	0.7696 mL	1.5392 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 96.01%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (254 KB) HNMR (319 KB) RP-HPLC (248 KB) LCMS (104 KB)

Handling Instructions (2659 KB)

References

[1]. Li X, et al., Anti-bdca2 antibody-drug conjugate and use thereof. WO2024140838.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5392 mL	7.6962 mL	15.3924 mL	38.4811 mL
	5 mM	0.3078 mL	1.5392 mL	3.0785 mL	7.6962 mL
	10 mM	0.1539 mL	0.7696 mL	1.5392 mL	3.8481 mL
	15 mM	0.1026 mL	0.5131 mL	1.0262 mL	2.5654 mL
	20 mM	0.0770 mL	0.3848 mL	0.7696 mL	1.9241 mL
	25 mM	0.0616 mL	0.3078 mL	0.6157 mL	1.5392 mL
	30 mM	0.0513 mL	0.2565 mL	0.5131 mL	1.2827 mL
	40 mM	0.0385 mL	0.1924 mL	0.3848 mL	0.9620 mL
	50 mM	0.0308 mL	0.1539 mL	0.3078 mL	0.7696 mL
	60 mM	0.0257 mL	0.1283 mL	0.2565 mL	0.6414 mL
	80 mM	0.0192 mL	0.0962 mL	0.1924 mL	0.4810 mL
	100 mM	0.0154 mL	0.0770 mL	0.1539 mL	0.3848 mL