Glutathione monoethyl ester

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Glutathione monoethyl ester is a glutathione derivative that can protect motor neuron cells NSC-34 from pathology damage caused by mutations in TDP-43, including reducing aggregation formation, nuclear clearance, reactive oxygen species generation, and cell death.

For research use only. We do not sell to patients.

Glutathione monoethyl ester Chemical Structure

CAS No. : 118421-50-4

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Description	Glutathione monoethyl ester is a glutathione derivative that can protect motor neuron cells NSC-34 from pathology damage caused by mutations in TDP-43, including reducing aggregation formation, nuclear clearance, reactive oxygen species generation, and cell death^[1].
Molecular Weight	335.38
Formula	C₁₂H₂₁N₃O₆S
CAS No.	118421-50-4
SMILES	O=C(C(NC(CCC(C(O)=O)N)=O)CS)NCC(OCC)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (263 KB) Handling Instructions (2659 KB)
References	[1]. Tong Chen, et al. Glutathione monoethyl ester prevents TDP-43 pathology in motor neuronal NSC-34 cells. Neurochem Int. 2018 Jan:112:278-287. [Content Brief]