Glycine-¹³C₂

Name: Glycine- 13 C 2
Brand: MedChemExpress
SKU: HY-Y0966S3
Rating: 4.5 (1 reviews)

Cat. No.: HY-Y0966S3 Purity: 99.10%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Glycine-¹³C₂ is the ¹³C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

For research use only. We do not sell to patients.

Glycine-<sup>13</sup>C<sub>2</sub> Chemical Structure

Glycine-¹³C₂ Chemical Structure

CAS No. : 67836-01-5

Size	Price	Stock	Quantity
10 mg	USD 55	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 110	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Glycine-¹³C₂:

Glycine In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

NMDA Receptor

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

77.05

Formula

¹³C₂H₅NO₂

CAS No.

67836-01-5

Appearance

Solid

Color

White to off-white

SMILES

N[13CH2][13C](O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 25 mg/mL (324.46 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	12.9786 mL	64.8929 mL	129.7859 mL
5 mM	2.5957 mL	12.9786 mL	25.9572 mL
10 mM	1.2979 mL	6.4893 mL	12.9786 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.10%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (248 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	12.9786 mL	64.8929 mL	129.7858 mL	324.4646 mL
	5 mM	2.5957 mL	12.9786 mL	25.9572 mL	64.8929 mL
	10 mM	1.2979 mL	6.4893 mL	12.9786 mL	32.4465 mL
	15 mM	0.8652 mL	4.3262 mL	8.6524 mL	21.6310 mL
	20 mM	0.6489 mL	3.2446 mL	6.4893 mL	16.2232 mL
	25 mM	0.5191 mL	2.5957 mL	5.1914 mL	12.9786 mL
	30 mM	0.4326 mL	2.1631 mL	4.3262 mL	10.8155 mL
	40 mM	0.3245 mL	1.6223 mL	3.2446 mL	8.1116 mL
	50 mM	0.2596 mL	1.2979 mL	2.5957 mL	6.4893 mL
	60 mM	0.2163 mL	1.0815 mL	2.1631 mL	5.4077 mL
	80 mM	0.1622 mL	0.8112 mL	1.6223 mL	4.0558 mL
	100 mM	0.1298 mL	0.6489 mL	1.2979 mL	3.2446 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.