Glyphosate-d₂-1

Cat. No.: HY-B0863S2: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Glyphosate-d₂-1 is the deuterium labeled Glyphosate[1]. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[2].

For research use only. We do not sell to patients.

Glyphosate-d<sub>2</sub>-1 Chemical Structure

Glyphosate-d₂-1 Chemical Structure

Size		Stock
1 mg		Get quote	Estimated Time of Arrival: December 31

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Glyphosate-d₂-1:

Glyphosate Get quote

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

171.09

Formula

C₃H₆D₂NO₅P

Unlabeled CAS

1071-83-6

SMILES

OC(C([2H])([2H])NCP(O)(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

H₂O : 13.89 mg/mL (81.19 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.8449 mL	29.2244 mL	58.4488 mL
5 mM	1.1690 mL	5.8449 mL	11.6898 mL
10 mM	0.5845 mL	2.9224 mL	5.8449 mL

View the Complete Stock Solution Preparation Table

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Greim H, et al. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015;45(3):185-208. [Content Brief]

[3]. Zhang JW, et al The toxic effects and possible mechanisms of glyphosate on mouse oocytes. Chemosphere. 2019 Dec237:124435. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.8449 mL	29.2244 mL	58.4488 mL	146.1219 mL
	5 mM	1.1690 mL	5.8449 mL	11.6898 mL	29.2244 mL
	10 mM	0.5845 mL	2.9224 mL	5.8449 mL	14.6122 mL
	15 mM	0.3897 mL	1.9483 mL	3.8966 mL	9.7415 mL
	20 mM	0.2922 mL	1.4612 mL	2.9224 mL	7.3061 mL
	25 mM	0.2338 mL	1.1690 mL	2.3380 mL	5.8449 mL
	30 mM	0.1948 mL	0.9741 mL	1.9483 mL	4.8707 mL
	40 mM	0.1461 mL	0.7306 mL	1.4612 mL	3.6530 mL
	50 mM	0.1169 mL	0.5845 mL	1.1690 mL	2.9224 mL
	60 mM	0.0974 mL	0.4871 mL	0.9741 mL	2.4354 mL
	80 mM	0.0731 mL	0.3653 mL	0.7306 mL	1.8265 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.