2. Anti-infection
  3. HIV
  4. GPS491

GPS491 (EC50 = 0.47 μM) suppresses expression of the HIV-1 structural protein Gag and alters HIV-1 RNA accumulation, decreasing the abundance of RNAs encoding the structural proteins while increasing levels of viral RNAs encoding the regulatory proteins.

For research use only. We do not sell to patients.

GPS491 Chemical Structure

GPS491 Chemical Structure

CAS No. : 2655502-29-5

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GPS491 Related Antibodies

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Description

GPS491 (EC50 = 0.47 μM) suppresses expression of the HIV-1 structural protein Gag and alters HIV-1 RNA accumulation, decreasing the abundance of RNAs encoding the structural proteins while increasing levels of viral RNAs encoding the regulatory proteins.

Cellular Effect
Cell Line Type Value Description References
PBMC CC50
2.51 μM
Compound: 29; GPS491
Cytotoxicity against human PBMC cells assessed as cell viability measured after 11 days by Viacount assay
Cytotoxicity against human PBMC cells assessed as cell viability measured after 11 days by Viacount assay
[PMID: 34795872]
Molecular Weight

397.32

Formula

C13H5F6N3OS2
CAS No.
SMILES

O=C(NC1=NC(C=CC(C(F)(F)F)=C2)=C2S1)C3=CN=C(C(F)(F)F)S3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GPS491 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GPS4912655502-29-5GPS 491GPS-491HIVHuman immunodeficiency virusInhibitorinhibitorinhibit

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