2. Anti-infection
  3. RABV
  4. GRP-60367

GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (GRP-60367 hydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

GRP-60367 Chemical Structure

GRP-60367 Chemical Structure

CAS No. : 1309241-34-6

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Other Forms of GRP-60367:

GRP-60367 Related Antibodies

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Description

GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains[1].

In Vitro

GRP-60367 inhibits entry of a subset of RABV strains. GRP-60367 shows specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC50s ranging from 2 to 52 nM on different host cell lines[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GRP-60367 Related Antibodies
Molecular Weight

353.46

Formula

C21H27N3O2
CAS No.
SMILES

CC1=C(OCCNC2CCN(C(C3=CC=NC=C3)=O)CC2)C=C(C)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GRP-60367 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GRP-603671309241-34-6GRP60367GRP 60367RABVRabies VirusrabiesvirusentrystrainInhibitorinhibitorinhibit

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GRP-60367
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HY-133735
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