2. Neuronal Signaling Stem Cell/Wnt PI3K/Akt/mTOR Apoptosis
  3. GSK-3 Tau Protein Apoptosis
  4. GSK-3β inhibitor 15

GSK-3β inhibitor 15 (Compound 54) is a GSK-3β inhibitor (IC50: 3.4 nM). GSK-3β inhibitor 15 inhibits Aβ1-42-induced GSK-3β and tau protein phosphorylation. GSK-3β inhibitor 15 inhibits LPS-induced iNOS expression. GSK-3β inhibitor 15 has neuroprotective effects on Aβ1-42-induced neurotoxicity. GSK-3β inhibitor 15 can be used for research of Alzheimer’s disease (AD).

For research use only. We do not sell to patients.

GSK-3β inhibitor 15 Chemical Structure

GSK-3β inhibitor 15 Chemical Structure

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GSK-3β inhibitor 15 Related Antibodies

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Description

GSK-3β inhibitor 15 (Compound 54) is a GSK-3β inhibitor (IC50: 3.4 nM). GSK-3β inhibitor 15 inhibits Aβ1-42-induced GSK-3β and tau protein phosphorylation. GSK-3β inhibitor 15 inhibits LPS-induced iNOS expression. GSK-3β inhibitor 15 has neuroprotective effects on Aβ1-42-induced neurotoxicity. GSK-3β inhibitor 15 can be used for research of Alzheimer’s disease (AD)[1].

Molecular Weight

352.41

Formula

C17H16N6OS
SMILES

O=C(CCN1N=CC(C)=C1)NC2=NNC3=C2SC(C4=CN=CC=C4)=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GSK-3β inhibitor 15 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK-3β inhibitor 15GSK-3Tau ProteinApoptosisGlycogen synthase kinase-3Glycogen synthase kinase 3iNOSLPStau hyperphosphorylationAβ1-42dyskinesiaAlzheimer’sADastrocytesmicrogliaInhibitorinhibitorinhibit

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