2. Metabolic Enzyme/Protease
  3. FXR
  4. GSK2324

GSK2324 (Compd 1c) is a FXR agonist for diabetes study, with an EC50 of 120 nM. GSK2324 exhibits t1/2 values of 84 min (mouse), 170 min (rat), 110 min (beagle) and 120 min (cyno), respectively.

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GSK2324 Chemical Structure

GSK2324 Chemical Structure

CAS No. : 1020567-30-9

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GSK2324 Related Antibodies

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Description

GSK2324 (Compd 1c) is a FXR agonist for diabetes study, with an EC50 of 120 nM. GSK2324 exhibits t1/2 values of 84 min (mouse), 170 min (rat), 110 min (beagle) and 120 min (cyno), respectively[1].

Molecular Weight

533.40

Formula

C29H22Cl2N2O4
CAS No.
SMILES

O=C(C1=NC2=CC=C(C3=CC=C(OCC4=C(C(C)C)ON=C4C5=C(Cl)C=CC=C5Cl)C=C3)C=C2C=C1)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GSK2324 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK23241020567-30-9GSK 2324GSK-2324FXRNR1H4diabetesdiet-induced obese (DIO) mouseInhibitorinhibitorinhibit

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