1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. GSK345931A

GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain.

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GSK345931A Chemical Structure

GSK345931A Chemical Structure

CAS No. : 869499-38-7

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Description

GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain[1].

IC50 & Target

EP1

 

Molecular Weight

403.83

Formula

C22H19ClNNaO3

CAS No.
SMILES

O=C(C1=CC=CC(C2=C(C3=C(OCC(C)C)C=CC(Cl)=C3)C=CC=C2)=N1)O[Na]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
GSK345931A
Cat. No.:
HY-111258
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