2. Autophagy Cell Cycle/DNA Damage
  3. Autophagy RAD51
  4. Guaiol (Standard)

Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions[4]

For research use only. We do not sell to patients.

Guaiol (Standard) Chemical Structure

Guaiol (Standard) Chemical Structure

CAS No. : 489-86-1

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Guaiol (Standard)489-86-1AutophagyRAD51A549 cellsH1299 cellsNon-small cell lung cancer (NSCLC) xenograft mouse modelAnti-cancer activityInhibitorinhibitorinhibit

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