2. GPCR/G Protein
  3. Adenylate Cyclase
  4. Guanylyl imidodiphosphate lithium

Guanylyl imidodiphosphate lithium  (Synonyms: Gpp(NH)p lithium)

Cat. No.: HY-137167 Purity: ≥98.0%
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Guanylyl imidodiphosphate (Gpp(NH)p) lithium, a non-hydrolyzable GTP analogue, increases adenylate cyclase activity.

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Guanylyl imidodiphosphate lithium Chemical Structure

Guanylyl imidodiphosphate lithium Chemical Structure

CAS No. : 64564-03-0

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1 mg USD 120 In-stock
5 mg USD 290 In-stock
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Based on 1 publication(s) in Google Scholar

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Guanylyl imidodiphosphate lithium Related Antibodies

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Description

Guanylyl imidodiphosphate (Gpp(NH)p) lithium, a non-hydrolyzable GTP analogue, increases adenylate cyclase activity[1][2].

Molecular Weight

545.93

Formula

C10H13Li4N6O13P3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]([C@@H]1O)[C@](O[C@@H]1CO[P](O[P](N[P](O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O)([H])N2C(NC(N)=NC3=O)=C3N=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (91.59 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8317 mL 9.1587 mL 18.3174 mL
5 mM 0.3663 mL 1.8317 mL 3.6635 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (251 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.8317 mL 9.1587 mL 18.3174 mL 45.7934 mL
5 mM 0.3663 mL 1.8317 mL 3.6635 mL 9.1587 mL
10 mM 0.1832 mL 0.9159 mL 1.8317 mL 4.5793 mL
15 mM 0.1221 mL 0.6106 mL 1.2212 mL 3.0529 mL
20 mM 0.0916 mL 0.4579 mL 0.9159 mL 2.2897 mL
25 mM 0.0733 mL 0.3663 mL 0.7327 mL 1.8317 mL
30 mM 0.0611 mL 0.3053 mL 0.6106 mL 1.5264 mL
40 mM 0.0458 mL 0.2290 mL 0.4579 mL 1.1448 mL
50 mM 0.0366 mL 0.1832 mL 0.3663 mL 0.9159 mL
60 mM 0.0305 mL 0.1526 mL 0.3053 mL 0.7632 mL
80 mM 0.0229 mL 0.1145 mL 0.2290 mL 0.5724 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Guanylyl imidodiphosphate lithium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Guanylyl imidodiphosphate64564-03-0Gpp(NH)pAdenylate CyclaseAdenylyl cyclasenon-hydrolyzableGTPadenylate cyclaseInhibitorinhibitorinhibit

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