2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. GW 590735 sodium

GW 590735 sodium is a potent and selective PPARα agonist with activity in regulating lipid metabolism. GW 590735 significantly increased high-density lipoprotein (HDL) cholesterol, decreased low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) cholesterol, and significantly reduced triglycerides. The maximum increases in HDL cholesterol for GW 590735 were 37%, 53% and 84%, respectively, compared with bezafibrate, torcetrapib and GW 590735.

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GW 590735 sodium Chemical Structure

GW 590735 sodium Chemical Structure

CAS No. : 343322-50-9

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Other Forms of GW 590735 sodium:

GW 590735 sodium Related Antibodies

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Description

GW 590735 sodium is a potent and selective PPARα agonist with activity in regulating lipid metabolism. GW 590735 significantly increased high-density lipoprotein (HDL) cholesterol, decreased low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) cholesterol, and significantly reduced triglycerides. The maximum increases in HDL cholesterol for GW 590735 were 37%, 53% and 84%, respectively, compared with bezafibrate, torcetrapib and GW 590735[1].

Molecular Weight

500.47

Formula

C23H20F3N2NaO4S
CAS No.
SMILES

O=C(C(C)(C)OC1=CC=C(CNC(C2=C(C)N=C(C3=CC=C(C(F)(F)F)C=C3)S2)=O)C=C1)O[Na]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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GW 590735 sodium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GW 590735343322-50-9GW590735GW-590735PPARPeroxisome proliferator-activated receptorsdyslipidemialipidimbalanceHDLctriglyceridesLDLcInhibitorinhibitorinhibit

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