2. Antibody-drug Conjugate/ADC Related
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  4. H-D-Aha-OH hydrochloride

H-D-Aha-OH (hydrochloride) is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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H-D-Aha-OH hydrochloride Chemical Structure

H-D-Aha-OH hydrochloride Chemical Structure

CAS No. : 1858224-26-6

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5 mg USD 55 In-stock
10 mg USD 85 In-stock
25 mg USD 170 In-stock
50 mg USD 270 In-stock
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H-D-Aha-OH hydrochloride Related Antibodies

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Description

H-D-Aha-OH (hydrochloride) is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Molecular Weight

180.59

Formula

C4H9ClN4O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[N-]=[N+]=NCC[C@@H](N)C(O)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1384.35 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.5374 mL 27.6870 mL 55.3741 mL
5 mM 1.1075 mL 5.5374 mL 11.0748 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.5374 mL 27.6870 mL 55.3741 mL 138.4351 mL
5 mM 1.1075 mL 5.5374 mL 11.0748 mL 27.6870 mL
10 mM 0.5537 mL 2.7687 mL 5.5374 mL 13.8435 mL
15 mM 0.3692 mL 1.8458 mL 3.6916 mL 9.2290 mL
20 mM 0.2769 mL 1.3844 mL 2.7687 mL 6.9218 mL
25 mM 0.2215 mL 1.1075 mL 2.2150 mL 5.5374 mL
30 mM 0.1846 mL 0.9229 mL 1.8458 mL 4.6145 mL
40 mM 0.1384 mL 0.6922 mL 1.3844 mL 3.4609 mL
50 mM 0.1107 mL 0.5537 mL 1.1075 mL 2.7687 mL
60 mM 0.0923 mL 0.4615 mL 0.9229 mL 2.3073 mL
80 mM 0.0692 mL 0.3461 mL 0.6922 mL 1.7304 mL
100 mM 0.0554 mL 0.2769 mL 0.5537 mL 1.3844 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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H-D-Aha-OH hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H-D-Aha-OH1858224-26-6ADC LinkerAntibody-drug conjugates linkerClickazideInhibitorinhibitorinhibit

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