1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. H-L-Tyr(2-azidoethyl)-OH hydrochloride

H-L-Tyr(2-azidoethyl)-OH hydrochloride 

Cat. No.: HY-151693 Purity: 99.88%
SDS COA Handling Instructions Technical Support

H-L-Tyr(2-azidoethyl)-OH hydrochloride is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH hydrochloride is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

H-L-Tyr(2-azidoethyl)-OH hydrochloride Chemical Structure

H-L-Tyr(2-azidoethyl)-OH hydrochloride Chemical Structure

CAS No. : 1567845-62-8

Size Price Stock Quantity
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of H-L-Tyr(2-azidoethyl)-OH hydrochloride:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

H-L-Tyr(2-azidoethyl)-OH hydrochloride is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH hydrochloride is a click chemistry reagent containing an azide group[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Molecular Weight

286.71

Formula

C11H15ClN4O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CC1=CC=C(C=C1)OCCN=[N+]=[N-])=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 11.67 mg/mL (40.70 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4878 mL 17.4392 mL 34.8784 mL
5 mM 0.6976 mL 3.4878 mL 6.9757 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.4878 mL 17.4392 mL 34.8784 mL 87.1961 mL
5 mM 0.6976 mL 3.4878 mL 6.9757 mL 17.4392 mL
10 mM 0.3488 mL 1.7439 mL 3.4878 mL 8.7196 mL
15 mM 0.2325 mL 1.1626 mL 2.3252 mL 5.8131 mL
20 mM 0.1744 mL 0.8720 mL 1.7439 mL 4.3598 mL
25 mM 0.1395 mL 0.6976 mL 1.3951 mL 3.4878 mL
30 mM 0.1163 mL 0.5813 mL 1.1626 mL 2.9065 mL
40 mM 0.0872 mL 0.4360 mL 0.8720 mL 2.1799 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

H-L-Tyr(2-azidoethyl)-OH hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
H-L-Tyr(2-azidoethyl)-OH hydrochloride
Cat. No.:
HY-151693
Quantity:
MCE Japan Authorized Agent: