2. PROTAC Anti-infection
  3. Ligands for Target Protein for PROTAC SARS-CoV Virus Protease
  4. H117

H117 is a PROTAC target protein ligand that can be used to synthesize PROTAC HP211206 (HY-170598). H117 has competitive binding and inhibition ability on SARS-CoV-2 main protease (Mpro) with an IC50 of 151.3 nM.

For research use only. We do not sell to patients.

H117 Chemical Structure

H117 Chemical Structure

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H117 Related Antibodies

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Description

H117 is a PROTAC target protein ligand that can be used to synthesize PROTAC HP211206 (HY-170598). H117 has competitive binding and inhibition ability on SARS-CoV-2 main protease (Mpro) with an IC50 of 151.3 nM[1].

IC50 & Target

IC50: 151.3 nM (SARS-CoV-2 Mpro) [1]
Molecular Weight

529.58

Formula

C24H37F2N5O6
SMILES

O=C(N1[C@H](C(N[C@H](C#N)C[C@H]2C(NCC2)=O)=O)C[C@@H](OC(F)F)C1)[C@H](C(C)(C)C)NC(OC(C)(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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H117 Related Classifications

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H117H 117H-117Ligands for Target Protein for PROTACSARS-CoVVirus ProteaseTarget Protein-binding MoietySARS coronavirusInhibitorinhibitorinhibit

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Product Name:
H117
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HY-170599
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