2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. H4R antagonist 2

H4R antagonist 2 (page 68), a Furo[3,2-d]pyrimidine derivative, is a potent H4R antagonist. H4R antagonist 2 can be used in research of rheumatoid arthritis.

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H4R antagonist 2 Chemical Structure

H4R antagonist 2 Chemical Structure

CAS No. : 1148115-99-4

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Based on 1 publication(s) in Google Scholar

H4R antagonist 2 Related Antibodies

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Description

H4R antagonist 2 (page 68), a Furo[3,2-d]pyrimidine derivative, is a potent H4R antagonist. H4R antagonist 2 can be used in research of rheumatoid arthritis[1].

Molecular Weight

259.31

Formula

C13H17N5O
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

NC1=NC(N2CC(NC)C2)=C(OC3=C4CCC3)C4=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 15 mg/mL (57.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8564 mL 19.2819 mL 38.5639 mL
5 mM 0.7713 mL 3.8564 mL 7.7128 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8564 mL 19.2819 mL 38.5639 mL 96.4097 mL
5 mM 0.7713 mL 3.8564 mL 7.7128 mL 19.2819 mL
10 mM 0.3856 mL 1.9282 mL 3.8564 mL 9.6410 mL
15 mM 0.2571 mL 1.2855 mL 2.5709 mL 6.4273 mL
20 mM 0.1928 mL 0.9641 mL 1.9282 mL 4.8205 mL
25 mM 0.1543 mL 0.7713 mL 1.5426 mL 3.8564 mL
30 mM 0.1285 mL 0.6427 mL 1.2855 mL 3.2137 mL
40 mM 0.0964 mL 0.4820 mL 0.9641 mL 2.4102 mL
50 mM 0.0771 mL 0.3856 mL 0.7713 mL 1.9282 mL
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H4R antagonist 2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H4R antagonist 21148115-99-4Histamine ReceptorInhibitorinhibitorinhibit

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