HBTU (Synonyms: N-HBTU)

Cat. No.: HY-Y0912 Purity: 98%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

HBTU is a coupling agent commonly used for the activation of free carboxylic acids during the solution and solid phase peptide synthesis.

For research use only. We do not sell to patients.

HBTU Chemical Structure

CAS No. : 94790-37-1

Size	Stock	Quantity
Free Sample (0.1 - 0.5 mg)	Apply Now
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
> 100 g	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

HBTU is a coupling agent commonly used for the activation of free carboxylic acids during the solution and solid phase peptide synthesis^[1].

Molecular Weight

379.24

Formula

C₁₁H₁₆F₆N₅OP

CAS No.

94790-37-1

Appearance

Solid

Color

White to off-white

SMILES

[F-][P+5](F)([F-2])([F-2])(F)[F-].CN(/C(N(C)C)=[N+]1N=[N+]([O-])C2=CC=CC=C2\1)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 200 mg/mL (527.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6369 mL	13.1843 mL	26.3685 mL
5 mM	0.5274 mL	2.6369 mL	5.2737 mL
10 mM	0.2637 mL	1.3184 mL	2.6369 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.80%

Select Batch:

Data Sheet (270 KB) SDS (454 KB)

COA (311 KB) RP-HPLC (109 KB)

Handling Instructions (2659 KB)

References

[1]. Sachitanand M Mali, et al. HBTU mediated 1-hydroxybenzotriazole (HOBt) conjugate addition: synthesis and stereochemical analysis of β-benzotriazole N-oxide substituted γ-amino acids and hybrid peptides. Org Biomol Chem. 2014 Nov 14;12(42):8462-72. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6369 mL	13.1843 mL	26.3685 mL	65.9213 mL
	5 mM	0.5274 mL	2.6369 mL	5.2737 mL	13.1843 mL
	10 mM	0.2637 mL	1.3184 mL	2.6369 mL	6.5921 mL
	15 mM	0.1758 mL	0.8790 mL	1.7579 mL	4.3948 mL
	20 mM	0.1318 mL	0.6592 mL	1.3184 mL	3.2961 mL
	25 mM	0.1055 mL	0.5274 mL	1.0547 mL	2.6369 mL
	30 mM	0.0879 mL	0.4395 mL	0.8790 mL	2.1974 mL
	40 mM	0.0659 mL	0.3296 mL	0.6592 mL	1.6480 mL
	50 mM	0.0527 mL	0.2637 mL	0.5274 mL	1.3184 mL
	60 mM	0.0439 mL	0.2197 mL	0.4395 mL	1.0987 mL
	80 mM	0.0330 mL	0.1648 mL	0.3296 mL	0.8240 mL
	100 mM	0.0264 mL	0.1318 mL	0.2637 mL	0.6592 mL

HBTU Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HBTU94790-37-1N-HBTUOthersFmocInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *

Organization Name *

Country or Region *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

HBTU (Synonyms: N-HBTU)

HBTU Related Antibodies

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

Molarity Calculator

Dilution Calculator