2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. HDAC-IN-68

HDAC-IN-68 (Compound 29) is a potent HDAC inhibitor that disrupts microtubule structure and inhibits tumor growth. HDAC-IN-68 significantly inhibits class I HDACs (HDAC1, HDAC2, HDAC3) with IC50 values of 5.1, 11.5 and 8.8 nM, respectively.

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HDAC-IN-68 Chemical Structure

HDAC-IN-68 Chemical Structure

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Other Forms of HDAC-IN-68:

HDAC-IN-68 Related Antibodies

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HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Description

HDAC-IN-68 (Compound 29) is a potent HDAC inhibitor that disrupts microtubule structure and inhibits tumor growth. HDAC-IN-68 significantly inhibits class I HDACs (HDAC1, HDAC2, HDAC3) with IC50 values of 5.1, 11.5 and 8.8 nM, respectively[1].

Molecular Weight

556.53

Formula

C27H24N8O6
SMILES

O=C(N1C2=C(OC)N=CC=C2)NC3=C1N=C(C4=CC=C(OCC)N=C4)N=C3C(NCC5=CC=C(C=C5)C(NO)=O)=O
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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HDAC-IN-68 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDAC-IN-68HDACHistone deacetylasesHDAC InhibitorInhibitorinhibitorinhibit

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