1. Others
  2. Others
  3. HDHD4-IN-1

HDHD4-IN-1 (compound 3) is a N-acetylneuraminate-9-phosphate phosphatase (HDHD4) inhibitor (IC50=11 μM). HDHD4-IN-1 can be used in the study of neurological diseases.

For research use only. We do not sell to patients.

HDHD4-IN-1 Chemical Structure

HDHD4-IN-1 Chemical Structure

CAS No. : 1447279-68-6

Size Price Stock Quantity
1 mg USD 520 In-stock
5 mg USD 1570 In-stock
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

HDHD4-IN-1 (compound 3) is a N-acetylneuraminate-9-phosphate phosphatase (HDHD4) inhibitor (IC50=11 μM). HDHD4-IN-1 can be used in the study of neurological diseases[1].

Molecular Weight

387.28

Formula

C12H22NO11P

CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=P(O)(O)CC[C@@H](O)[C@H]([C@@]1([H])[C@@H]([C@H](C[C@](O)(O1)C(O)=O)O)NC(C)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (258.21 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5821 mL 12.9106 mL 25.8211 mL
5 mM 0.5164 mL 2.5821 mL 5.1642 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.5821 mL 12.9106 mL 25.8211 mL 64.5528 mL
5 mM 0.5164 mL 2.5821 mL 5.1642 mL 12.9106 mL
10 mM 0.2582 mL 1.2911 mL 2.5821 mL 6.4553 mL
15 mM 0.1721 mL 0.8607 mL 1.7214 mL 4.3035 mL
20 mM 0.1291 mL 0.6455 mL 1.2911 mL 3.2276 mL
25 mM 0.1033 mL 0.5164 mL 1.0328 mL 2.5821 mL
30 mM 0.0861 mL 0.4304 mL 0.8607 mL 2.1518 mL
40 mM 0.0646 mL 0.3228 mL 0.6455 mL 1.6138 mL
50 mM 0.0516 mL 0.2582 mL 0.5164 mL 1.2911 mL
60 mM 0.0430 mL 0.2152 mL 0.4304 mL 1.0759 mL
80 mM 0.0323 mL 0.1614 mL 0.3228 mL 0.8069 mL
100 mM 0.0258 mL 0.1291 mL 0.2582 mL 0.6455 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

HDHD4-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
HDHD4-IN-1
Cat. No.:
HY-157727
Quantity:
MCE Japan Authorized Agent: