2. Others Metabolic Enzyme/Protease
  3. Biochemical Assay Reagents Heme Oxygenase (HO)
  4. Hemoglobin

Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin is an inducer of HO-1. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. Hemoglobin absorbs unneeded oxygen in tissues, as an antioxidant.

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Hemoglobin Chemical Structure

Hemoglobin Chemical Structure

CAS No. : 9008-02-0

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Hemoglobin Related Antibodies

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Description

Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin is an inducer of HO-1. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. Hemoglobin absorbs unneeded oxygen in tissues, as an antioxidant[1].

In Vitro

Hemoglobin (1-50 μM, 6 h) increases α1-microglobulin and reactive oxygen species in HepG2 cells[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Hemoglobin Related Antibodies
In Vivo

Hemoglobin (300 mg/k, i.v. at 16 h before LPS) provides protection against LPS induced lethal endotoxemia in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: LPS induced endotoxemia rat model[2]
Dosage: 300 mg/kg
Administration: i.v., at 16 h before LPS treatment (40 mg/kg, i.v,)
Result: Increased rat survival.
Showed significant attenuation of neutrophil alveolitis ( > 80 %) at 24 h after LPS injection.
Increased HO-1 expression and activity in rat lung.
Clinical Trial
CAS No.
Appearance

Solid

Color

Brown to reddish brown

SMILES

[Hemoglobin]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O : 20 mg/mL (Need ultrasonic)

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Purity & Documentation

SDS (251 KB)

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Hemoglobin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hemoglobin9008-02-0Biochemical Assay ReagentsHeme Oxygenase (HO)Heme OxygenaseInhibitorinhibitorinhibit

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