Herbicidin A 

Herbicidin A is an adenosine-derived nucleoside antibiotic, but also is a herbicide against dicotyledonous plants. Herbicidin A can be isolated from Streptomyces scopuliridis M40^[1][2].

Herbicidin A is the most extensively decorated herbicidin to date, which has a 5-hydroxytiglyl group at C8^[1].
The precursors for herbicidin biosynthesis are D-glucose, D-ribose, Lisoleucine, and L-methionine^[1].
Herbicidins are selective herbicide against dicotyledonous plants and inhibit the germination of Chinese cabbage and rice seeds^[1].
Herbicidins can protect rice plants from leaf blight and also exhibit antialgal and antifungal activities^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

551.50

C₂₃H₂₉N₅O₁₁

55353-31-6

O[C@]12[C@@](O[C@@H]([C@H]([C@@H]2OC(/C(CO)=C/C)=O)O)C(OC)=O)([H])C[C@]3([H])[C@]([C@H]([C@H](N4C5=NC=NC(N)=C5N=C4)O3)OC)([H])O1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Lin GM, et al. Identification and Interrogation of the Herbicidin Biosynthetic Gene Cluster: First Insight into the Biosynthesis of a Rare Undecose Nucleoside Antibiotic. J Am Chem Soc. 2017 Nov 22;139(46):16450-16453.  [Content Brief]

  [2]. Ha S, et al. Optimization of Herbicidin A Production in Submerged Culture of Streptomyces scopuliridis M40. J Microbiol Biotechnol. 2017 May 28;27(5):947-955.  [Content Brief]