2. PROTAC
  3. PROTAC Linkers
  4. Hexaethylene glycol monomethyl ether

Hexaethylene glycol monomethyl ether 

Cat. No.: HY-W042625 Purity: 98.77%
SDS COA Handling Instructions

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Hexaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Hexaethylene glycol monomethyl ether Chemical Structure

Hexaethylene glycol monomethyl ether Chemical Structure

CAS No. : 23601-40-3

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Based on 1 publication(s) in Google Scholar

Hexaethylene glycol monomethyl ether Related Antibodies

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Description

Hexaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Hexaethylene glycol monomethyl ether Related Antibodies
Molecular Weight

296.36

Formula

C13H28O7
CAS No.
Appearance

Liquid (Density: 1,08 g/cm3)

Color

Colorless to light yellow

SMILES

COCCOCCOCCOCCOCCOCCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation

Purity: 98.77%

SDS (393 KB)

COA (239 KB) HNMR (114 KB) GC (223 KB)

Handling Instructions (2659 KB)
References
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Hexaethylene glycol monomethyl ether Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hexaethylene glycol monomethyl ether23601-40-3PROTAC LinkersInhibitorinhibitorinhibit

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