2. Protein Tyrosine Kinase/RTK
  3. Bcr-Abl
  4. HG-7-86-01

HG-7-86-01 (Compound 26) is type II tyrosine kinase inhibitor. HG-7-86-01 has anti-proliferative activity.

For research use only. We do not sell to patients.

HG-7-86-01 Chemical Structure

HG-7-86-01 Chemical Structure

CAS No. : 1258391-14-8

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5 mg USD 205 In-stock
10 mg USD 325 In-stock
25 mg USD 650 In-stock
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Based on 1 publication(s) in Google Scholar

HG-7-86-01 Related Antibodies

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Description

HG-7-86-01 (Compound 26) is type II tyrosine kinase inhibitor. HG-7-86-01 has anti-proliferative activity[1].

Molecular Weight

562.57

Formula

C28H21F3N6O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1CC1)NC2=NC3=CC=C(C4=CC=CC(C(NC5=CC(N6C=NC(C)=C6)=CC(C(F)(F)F)=C5)=O)=C4)N=C3S2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (8.89 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7776 mL 8.8878 mL 17.7756 mL
5 mM 0.3555 mL 1.7776 mL 3.5551 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7776 mL 8.8878 mL 17.7756 mL 44.4389 mL
5 mM 0.3555 mL 1.7776 mL 3.5551 mL 8.8878 mL
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HG-7-86-01 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HG-7-86-011258391-14-8Bcr-Abltype II tyrosine kinaseanti-proliferativeInhibitorinhibitorinhibit

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