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  6. Anti-Cancer Compound Library
Anti-Cancer Compound Library

Cat. No.: HY-L025

Cancer is the second leading cause of death globally and seriously threatens human health. A neoplasm and malignant tumor are other common names for cancer. Disruption of the normal regulation of cell-cycle progression and division lies at the heart of the events leading to cancer. Target therapy, which targets proteins that control how cancer cells grow, divide and spread, plays an important role in cancer treatment. Recent studies mainly focus on targeting the key proteins for cancer surviving, cancer stem cells, the tumor microenvironment, tumor immunology, etc.

MCE designs a unique collection of 8,510 anti-cancer compounds that target kinases, cell cycle key components, tumorigenesis related signaling pathways, etc. MCE Anti-cancer compound library is a useful tool for anti-cancer drug screening.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Description & Advantages

•   A unique collection of 8,510 bioactive anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS).

•   Targets include kinases, cell cycle key components, tumorigenesis related signaling pathways, popular targets in epigenetic studies, and more.

•   A useful tool for the discovery of anti-cancer drugs.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   Validated NMR and HPLC to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details

Formulation:

A collection of 8,510 anti-cancer compounds supplied as pre-dissolved Solutions or Solid
Solution: 8,290 compounds supplied in 10 mM solution, 190 compounds supplied in 2 mM solution, 30 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

CDK (238)

EGFR (205)

PI3K (178)

NF-κB (167)

VEGFR (148)

Akt (121)

HDAC (120)

Fungal (115)

COX (105)

mTOR (104)

STAT (101)

HIV (99)

PARP (99)

Ras (95)

JAK (85)

FLT3 (84)

FGFR (82)

HSP (79)

PDGFR (79)

ERK (75)

MMP (75)

Wnt (74)

Src (67)

PKC (58)

c-Kit (57)

PPAR (57)

Raf (57)

Btk (50)

MEK (49)

AMPK (44)

FAK (38)

GSK-3 (38)

mAChR (38)

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  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
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    Product Name:
    Anti-Cancer Compound Library
    Cat. No.:
    HY-L025
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack

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