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  6. Anti-Hematopathy Compound Library
Anti-Hematopathy Compound Library

Cat. No.: HY-L171

Hematopathy, also known as hematopoietic system diseases, are a class of diseases that hematopoietic system has abnormal changes. Common hematopathy include: aplastic anemia, myeloproliferative diseases, thalassemia, leukemia, lymphoma, myeloma and hemophilia, etc. In recent years, treatments for hematopathy have been developed. In particular, the treatment of malignant hematopathy developed from chemotherapy, radiotherapy, bone marrow development to immunotherapy, induced differentiation therapy, cell therapy, gene therapy and hematopoietic stem cell transplantation. Although these therapies have greatly improved the survival rate of patients, there are still problems such as low cure rate and easy recurrence in the treatment of hematopathy. Therefore, it is of great significance to actively search for new hematopathy therapeutic drugs.

MCE designs a unique collection of 2,930 anti-hematopathy small molecules, which is an effective tool for development and research of anti-hematopathy compounds.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Description & Advantages

•   A unique collection of 2,930 anti-hematopathy compounds for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of anti-hematopathy diseases compounds such as aplastic anemia, mediterranean anemia, leukemia, haemophilia, etc.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

Product Details

Formulation:

A collection of 2,930 bioactive compounds related to hematopathy supplied as pre-dissolved Solutions or Solid.
Solution: 2,868 compounds supplied in 10 mM solution, 57 compounds supplied in 2 mM solution, 5 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

NF-κB (264)

CDK (262)

PI3K (182)

VEGFR (160)

HDAC (136)

JAK (126)

Akt (114)

STAT (110)

mTOR (100)

Ras (97)

FLT3 (84)

PDGFR (70)

Btk (64)

c-Kit (62)

HIV (43)

FGFR (39)

EGFR (38)

Src (33)

COX (30)

ERK (26)

GSK-3 (26)

AMPK (21)

HSV (18)

JNK (18)

c-Fms (15)

HSP (13)

PKC (13)

Raf (13)

RET (13)

Syk (13)

MMP (11)

IRAK (10)

PPAR (10)

PARP (9)

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  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
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    Product Name:
    Anti-Hematopathy Compound Library
    Cat. No.:
    HY-L171
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack

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