Hirsutanonol 5-O-β-D-glucopyranoside (Synonyms: Hirsutanonol 5-O-glucoside)

Cat. No.: HY-N4043: FAQs
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Hirsutanonol 5-O-glucoside is a diarylheptanoid derivatives that can be isolated from Alnus hirsuta. Hirsutanonol 5-O-glucoside exhibits significant hepatoprotective effects against t-BHP-induced toxicity in HepG2 cells with 42.8% protection.

For research use only. We do not sell to patients.

Hirsutanonol 5-O-β-D-glucopyranoside Chemical Structure

CAS No. : 93915-36-7

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Description

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	10 μM Compound: 4	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 0.5 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 0.5 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis	[PMID: 33422907]
RAW264.7	IC₅₀	29.4 μg/mL Compound: 4	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced NO production incubated for 24 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced NO production incubated for 24 hrs by Griess assay	[PMID: 33422907]
RAW264.7	IC₅₀	33.7 μg/mL Compound: 4	Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced COX2 production preincubated for 2 hrs followed by IFN-gamma and LPS stimulation and measured after 16 hrs by spectrophotometric analysis Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced COX2 production preincubated for 2 hrs followed by IFN-gamma and LPS stimulation and measured after 16 hrs by spectrophotometric analysis	[PMID: 33422907]

Molecular Weight

508.51

Formula

C₂₅H₃₂O₁₁

CAS No.

93915-36-7

SMILES

OC1=C(O)C=CC(CC[C@@H](CC(CCC2=CC(O)=C(O)C=C2)=O)O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)CO)=C1

Structure Classification

Initial Source

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Park D, et al. A new diarylheptanoid glycoside from the stem bark of Alnus hirsuta and protective effects of diarylheptanoid derivatives in human HepG2 cells. Chem Pharm Bull (Tokyo). 2010 Feb;58(2):238-41. [Content Brief]

Hirsutanonol 5-O-β-D-glucopyranoside Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hirsutanonol 5-O-β-D-glucopyranoside93915-36-7Hirsutanonol 5-O-glucosideOthersDiarylheptanoid derivativesHepG2Alnus hirsuteHepatoprotective effectsInhibitorinhibitorinhibit

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