2. Metabolic Enzyme/Protease
  3. HIV Integrase
  4. HIV-1 integrase inhibitor 7

HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor, with an IC50 of 33.3 nM.

For research use only. We do not sell to patients.

HIV-1 integrase inhibitor 7 Chemical Structure

HIV-1 integrase inhibitor 7 Chemical Structure

CAS No. : 204268-03-1

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HIV-1 integrase inhibitor 7 Related Antibodies

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Description

HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor, with an IC50 of 33.3 nM[1].

Cellular Effect
Cell Line Type Value Description References
CEM-SS EC50
16 μM
Compound: 6
Compound was evaluated for the cytoprotection by XTT cytoprotection assay through the NCI AIDS Screen
Compound was evaluated for the cytoprotection by XTT cytoprotection assay through the NCI AIDS Screen
[PMID: 10212126]
CEM-SS IC50
50 μM
Compound: 6
Compound was evaluated for the cytoprotection of CEM-SS cells by XTT cytoprotection assay through the NCI AIDS Screen
Compound was evaluated for the cytoprotection of CEM-SS cells by XTT cytoprotection assay through the NCI AIDS Screen
[PMID: 10212126]
MT4 EC50
10.1 μM
Compound: 6
Concentration of compound required to protect 50% of MT-4 cells against retroviral cytopathic effects by HIV-2 (ROD)
Concentration of compound required to protect 50% of MT-4 cells against retroviral cytopathic effects by HIV-2 (ROD)
[PMID: 10212126]
MT4 EC50
4.1 μM
Compound: 6
Concentration of compound required to protect 50% of MT-4 cells against retroviral cytopathic effects by HIV-1 (IIIa)
Concentration of compound required to protect 50% of MT-4 cells against retroviral cytopathic effects by HIV-1 (IIIa)
[PMID: 10212126]
MT4 IC50
47.1 μM
Compound: 6
Concentration of compound required to reduce MT-4 cell viability by 50%
Concentration of compound required to reduce MT-4 cell viability by 50%
[PMID: 10212126]
Molecular Weight

642.52

Formula

C30H26O16
CAS No.
SMILES

O=C(O)[C@H](OC(/C=C/C1=CC=C(OC(C)=O)C(OC(C)=O)=C1)=O)[C@@H](OC(/C=C/C2=CC=C(OC(C)=O)C(OC(C)=O)=C2)=O)C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HIV-1 integrase inhibitor 7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HIV-1 integrase inhibitor 7204268-03-1HIV IntegraseintegraseviralenzymeInhibitorinhibitorinhibit

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HIV-1 integrase inhibitor 7
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