HMBPP lithium (Synonyms: (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium)

Cat. No.: HY-134891 Purity: ≥95.0%: FAQs
Data Sheet SDS COA Handling Instructions

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HMBPP (lithium) is an activator for human Vγ9/Vδ2 T cells. HMBPP exhibits phagostimulant property in mosquitos.

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HMBPP lithium Chemical Structure

CAS No. : 396726-03-7

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1 mg	USD 1160	In-stock	Estimated Time of Arrival: December 31
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Description	HMBPP (lithium) is an activator for human Vγ9/Vδ2 T cells. HMBPP exhibits phagostimulant property in mosquitos^[1]^[2].
Molecular Weight	279.89
Formula	C₅H₉Li₃O₈P₂
CAS No.	396726-03-7
Appearance	Solid
Color	White to off-white
SMILES	O=P(OP(O[Li])(O[Li])=O)(O[Li])OC/C=C(C)/CO
Structure Classification	Others
Initial Source	Microorganisms Escherichia coli
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation	Purity: ≥95.0% Select Batch: Data Sheet (265 KB) SDS (392 KB) COA (245 KB) Handling Instructions (2659 KB)
References	[1]. Hintz M, et al., Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human gammadelta T cells in Escherichia coli. FEBS Lett. 2001 Dec 7;509(2):317-22. [Content Brief] [2]. Stromsky VE, et al., Plasmodium metabolite HMBPP stimulates feeding of main mosquito vectors on blood and artificial toxic sources. Commun Biol. 2021 Oct 7;4(1):1161. [Content Brief]

HMBPP lithium Related Classifications

Inflammation/Immunology Infection

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HMBPP396726-03-7(E)-4-Hydroxy-3-methyl-but-2-enyl diphosphateNuclear Factor of activated T Cells (NFAT)MosquitophagostimulantAnopheles coluzziiAn. arabiensisAn. gambiae s.s.Aedes aegyptiCulex pipiensCulex torrentiumInhibitorinhibitorinhibit

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HMBPP lithium (Synonyms: (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium)

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