2. Apoptosis
  3. Apoptosis
  4. HOE 689

HOE 689 (Ramnodigin) is an analog of Digitoxin (HY-B1357). HOE 689 exhibits cytotoxicity to lung cancer cells and induces apoptosis in cancer cell NCI-H460 with an IC50 of 52 nM.

For research use only. We do not sell to patients.

HOE 689 Chemical Structure

HOE 689 Chemical Structure

CAS No. : 33156-28-4

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HOE 689 Related Antibodies

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Description

HOE 689 (Ramnodigin) is an analog of Digitoxin (HY-B1357). HOE 689 exhibits cytotoxicity to lung cancer cells and induces apoptosis in cancer cell NCI-H460 with an IC50 of 52 nM[1].

Molecular Weight

488.66

Formula

C29H44O6
CAS No.
SMILES

O[C@@]12[C@@]3([H])[C@@](CC[C@@]1([C@@H](C(CO4)=CC4=O)CC2)C)([H])[C@@]5([C@](C[C@H](CC5)O[C@@H]6O[C@H]([C@@H](CC6)O)C)([H])CC3)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HOE 689 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HOE 68933156-28-4RamnodiginHOE689HOE-689ApoptosisNCI-H460DigitoxinrhamnoseamicetoseInhibitorinhibitorinhibit

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