1. PROTAC Anti-infection
  2. PROTACs Bacterial
  3. Homo-BacPROTAC6

Homo-BacPROTAC6 is a ClpC1NTD BacPROTAC degrader and can targets ClpC2. Homo-BacPROTAC7 efficiently kill M. tuberculosis.

For research use only. We do not sell to patients.

Homo-BacPROTAC6 Chemical Structure

Homo-BacPROTAC6 Chemical Structure

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Description

Homo-BacPROTAC6 is a ClpC1NTD BacPROTAC degrader and can targets ClpC2. Homo-BacPROTAC7 efficiently kill M. tuberculosis[1].

In Vitro

Homo-BacPROTAC6 inhibits M. tuberculosis growth with IC50s of 0.34 μM and 0.23 μM against WT and ∆clpC2 strains, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2170.63

Formula

C112H164N22O22

SMILES

O=C(N[C@H](C(N(C)[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CC1=CN(CC2=CN(CCOCCOCCOCCOCCN3C=C(CN4C=C(C[C@@H]5NC([C@@H](NC([C@@H](N(C)C([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@H](C[C@@H](C)CO)N(C)C5=O)=O)C)=O)[C@@H](C6=CC=CC=C6)OC)=O)=O)CC(C)C)=O)C(C)C)=O)C7=C4C=CC=C7)N=N3)N=N2)C8=C1C=CC=C8)C9=O)=O)=O)CC(C)C)=O)C(C)C)[C@@H](NC([C@H](C)NC([C@H](C[C@H](CO)C)N9C)=O)=O)[C@H](OC)C%10=CC=CC=C%10

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Homo-BacPROTAC6 Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Homo-BacPROTAC6
Cat. No.:
HY-153571
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