2. GPCR/G Protein
  3. Platelet-activating Factor Receptor (PAFR)
  4. Homoeriodictyol 7-O-β-D-glucoside

Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. Homoeriodictyol 7-O-β-D-glucoside inhibits human and rabbit platelet aggregation induced by PAF, with an IC50 of 0.8 μM.

For research use only. We do not sell to patients.

Homoeriodictyol 7-O-β-D-glucoside Chemical Structure

Homoeriodictyol 7-O-β-D-glucoside Chemical Structure

CAS No. : 14982-11-7

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Based on 1 publication(s) in Google Scholar

Homoeriodictyol 7-O-β-D-glucoside Related Antibodies

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Description

Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. Homoeriodictyol 7-O-β-D-glucoside inhibits human and rabbit platelet aggregation induced by PAF, with an IC50 of 0.8 μM[1].

IC50 & Target

platelet-activating factor[1]
Cellular Effect
Cell Line Type Value Description References
RAW264.7 IC50
23.4 μM
Compound: 11
Antiinflammatory activity against mouse RAW264.7 cells assessed as Inhibition of LPS-induced nitric oxide production after 24 hrs by ELISA
Antiinflammatory activity against mouse RAW264.7 cells assessed as Inhibition of LPS-induced nitric oxide production after 24 hrs by ELISA
[PMID: 20121165]
In Vitro

Homoeriodictyol 7-O-β-D-glucoside significantly inhibits human and rabbit platelet aggregation induced by PAF, but has no inhibitory effect on platelet aggregation induced by Adenosine diphosphate (ADP)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Homoeriodictyol 7-O-β-D-glucoside Related Antibodies
Molecular Weight

464.42

Formula

C22H24O11
CAS No.
SMILES

O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)C=C2O[C@H](C4=CC(OC)=C(C=C4)O)C1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Homoeriodictyol 7-O-β-D-glucoside Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Homoeriodictyol 7-O-β-D-glucoside14982-11-7Platelet-activating Factor Receptor (PAFR)plateletactivatingfactorPAFaggregationInhibitorinhibitorinhibit

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